Guo-Xiang Yang, MD, PhD – Department of Internal Medicine

Role of Environmental Chemicals in the Pathogenesis of Autoimmune Disease

Although it is well known that environmental pollution poses significant health hazards, data on the environment and human autoimmunity are limited. This study will examine the effects of a group of well-defined environmental pollutants on the immune functions of patients with systemic lupus erythematosus (SLE), a classical, systemic autoimmune disease.

Data from this work will enhance our understanding on how chemical pollutants contribute to the development of SLE and provide insights on the etiology and clinical management of environmental-triggered autoimmune disease.